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Scientific Programme

Last Update: April 7. 2016. Download links for selected presentations are now available (login required!).

Preliminary Scientific Programme

Plenary Symposia will each be introduced and moderated by the indicated chair person. Lecturers will then discuss their methodologies, discuss these in detail with the students and then show their most recent Systems Biology discoveries.

Programme grid

Program grid
The programme grid can also be downloaded as a PDF.

Detailed Programme

Sunday, February 28, 2016
Pre Course Teaching (optional, all day)
For more information please check the precourse info page.
PC-01 Wolfram Liebermeister & Elad Noor Introduction into modeling of biological systems
(A brief introduction to biochemical network modelling can be found here.) FileLogin required
PC-02 Karl Kuchler Molecular genetics in a nutshell (cancelled)
CellDesigner Computer Practical:
  Akira Funahashi CellDesigner FileLogin required
Opening Keynote Lecture (evening)
  Chair: Edda Klipp
Brenda Andrews (CA) Genetic Networks

 

Monday, February 29, 2016
Symposium:

Cellular decision making
  Chair: Bas Teusink
Bela Novak (UK) Dynamics of cell cycle decisions
Genevieve Dupont (BE) Modeling approaches of time and space organization in cell biology. Applications to calcium signaling and cell fate specification FileLogin required
Marian Walhout (US) Nutritional Regulatory Networks

 

Tuesday, March 1, 2016
Symposium:

Protein networks
  Chair: Matthias Heinemann
Paola Picotti (CH) Probing protein network responses by quantitative proteomics approaches
Ron Milo (IL) Cell Biology by the Numbers FileLogin required
Anne-Claude Gingras (CA) Mapping interactions in a human cell by quantitative proteomics

 

Wednesday, March 2, 2016
Symposium:

From molecules to functional phenotypes
  Chair: Frank Bruggeman
Ursula Klingmüller (DE) From molecules to patients or the usefulness of dynamic pathway models (cancelled)
Uwe Sauer (CH) Coordination of Metabolism FileLogin required
Bernd Bodenmiller (CH) Systems level analysis of single cell phenotypes

 

Thursday March 3, 2016
Symposium:

Medical systems biology
  Chair: Michael Savageau
Yuichi Sugiyama (JP) Use of physiologically and mechanism based pharmacokinetic modeling in new drug discovery and development:  Predicting target tissue exposure from in vitro to in vivo FileLogin required

Alistair Brown (UK)

Managing stress in a fungal pathogen

Jens Timmer (DE)

Uncertainty Analysis in Systems Biology FileLogin required

 

Friday, March 4, 2016
Symposium:

SB in space and time
  Chair: Marcus Krantz
Jan Ellenberg (DE)
Systems biology of human cell division using light microscopy
Alejandro Colman-Lerner (AR)
Information processing and robustness in signal transduction FileLogin required
Ron Weiss (US) Mammalian synthetic biology: from parts to modules to therapeutic systems
Closing Lecture
  Chair: Uwe Sauer
Chris Sander (US) Systems Biology in action: Design of cancer combination therapy

Blackboard Teaching

In Black board teaching sessions teachers carefully selected for this mode will explain in the simplest possible terms and in highly interactive mode, principles and methodologies. Detailed information about the Blackboard Teaching & Computer Practicals wil be posted here.

Blackboard Teaching (Monday, Wednesday, Thursday afternoon)
Bas Teusink (NL) Genome-scale metabolic models, their construction and analysis
Matthias Heinemann (NL) Experimental methods for single cell analyses
Frank Bruggeman Origins of stochasticity in single cells: theory and experimental illustrations
Michael Savageau (US) Modeling strategies for addressing the genotype-phenotype challenge FileLogin required
Elad Noor (CH) Introduction to enzyme regulation and cost using kinetic models FileLogin required
Marcus Krantz (DE) Building and validating (large) mechanistic models of signal transduction
Debora Marks Statistical inference on genomic sequences to solve challenges in systems biology

Computer Practicals

Computer practicals will demonstrate modern modeling and data analysis tools hand on. Students are advised to bring their own laptops to the practicals as the organizers do not provide laptops. The software used for the practicals will be made available at the course site. Detailed information about the Blackboard Teaching & Computer Practicals can be found here.

Computer Practicals (Sunday*, Monday, Wednesday, Thursday afternoon)
Ursula Kummer (DE),
Sven Sahle (DE),
Pedro Mendes (UK, US)
Introduction into modeling with COPASI
Akira Funahashi (JP) CellDesigner* FileLogin required
Clemens Kreutz (DE),
Bernhard Steiert (DE)
Statistics and numerics for dynamical modeling FileLogin required
* IMPORTANT!: The computer practicals for CellDesigner by Akira Funahashi will take place on Sunday and Monday. All other courses take place on two of the days from Monday, Wednesday or Thursday.

Software for Computer Practicals:

Please make sure that your Laptop fullfills the requirements for your selected computer practicals and that any required software is installed prior to the practicals.

Precourse Teaching

On Sunday February 28, two parallel preparatory courses will be held from morning until evening. These courses are intended to teach the basics to students who are not firm in the respective topics. For more information please check the precourse info page.

Registering for one of these courses will require an extra night’s accommodation and meals, which we will book for you and it will require us to charge an extra registration fee (€ 150). Please be aware that the number of places for these preparatory courses are limited and acceptance for these courses will be communicated by the organizers.

Software for Preparatory Courses:

Please make sure that your Laptop fullfills the following requirements for your selected Preparatory Course and that any required software is installed prior to the Preparatory Course:

TBA

Oral Presentations

Selected "Short Talks" will be delivered during afternoon sessions by principal investigators, graduate students and postdocs. These presentations will be selected by the Scientific Advisory Board on the basis of submitted abstracts. All selected speakers will be notified by e-mail to submit study material in PDF-format about their talk for the students.

Please deliver your presentation on a USB-Stick at least two hours before your talk is sheduled. We will supply OS X 10.8 and Windows 7 Laptops for your presentations. Available software for presentations includes Adobe Acrobat 10, Keynote 2008 (OS X), Microsoft Powerpoint (Win: 2010, OS X: 2011), OpenOffice 3.2 as well as Quicktime and common audio/video codecs. The preferred presentation type is Powerpoint. For any special requirements please contact the meeting office.

Poster Sessions

The poster session represents a vital part of the SysBio Course. All abstracts not selected for oral presentations will be on display as posters during the entire course to provide ample time for informal discussions among students, participants and lecturers. In small-group sessions lecturers will provoke intensive discussions about the posters and about careers and research plans with the individual students.

Poster size: The maximum allowed size for a poster is 120cm height by 90cm width (=47 x 35 inches). The posters will by attached to the boards via adhesive tape, which will be supplied by the organizer. If you have not been notified about giving an oral presentation, you have been selected for a poster presentation.

Young Investigator Awards

All abstracts with graduate students or postdoctoral fellows as first authors are subject to scientific evaluation by selected members of the SAB. The best abstract in each topic shall receive the "SysBio Young Investigator Award".